Based on Mikhail Bulgakov's novel of the same name.
It’s 1924, Moscow. Professor Preobrazhensky conceives a remarkable experiment. He transplants human pituitary and seminal glands to a stray dog that has moved into his apartment. The results of the operation are incredible. The dog, Sharikov physically transforms into a man who is able to speak. Despite the initial success of the experiment, though, things quickly take a turn for the worst. Sharikov exhibits the worst character traits of the recently deceased drunk brawler from where his transplanted glands came.